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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCSH
All Species:
1.52
Human Site:
T298
Identified Species:
2.78
UniProt:
P14314
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14314
NP_001001329.1
528
59425
T298
A
P
S
A
P
D
L
T
E
P
K
E
E
Q
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542057
593
66107
L353
P
A
P
S
E
P
D
L
T
E
P
K
E
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
O08795
521
58774
K298
V
P
E
E
T
E
P
K
E
E
K
P
P
V
L
Rat
Rattus norvegicus
NP_001100276
525
59200
K297
V
P
E
V
T
E
P
K
E
E
K
L
P
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510649
692
76488
G337
L
V
E
A
P
A
G
G
N
P
D
P
V
P
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086185
514
57354
P293
E
T
D
A
L
P
V
P
P
I
E
Q
P
T
E
Zebra Danio
Brachydanio rerio
NP_957347
529
59566
V303
V
E
T
P
V
D
E
V
K
E
P
V
V
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609844
548
61521
Q317
Q
P
E
E
V
A
Q
Q
P
E
V
T
T
E
S
Honey Bee
Apis mellifera
XP_625125
493
56012
V262
F
D
K
D
R
N
G
V
V
S
E
E
E
A
M
Nematode Worm
Caenorhab. elegans
NP_496073
507
58044
L280
Q
S
L
M
Y
D
R
L
K
T
A
K
R
T
H
Sea Urchin
Strong. purpuratus
XP_789169
523
60041
Q264
A
L
K
Q
Q
E
G
Q
E
Q
Q
G
E
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146004
602
67827
T289
P
Q
E
S
A
A
P
T
I
E
K
D
S
S
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04924
702
79889
L480
I
F
S
S
R
K
D
L
V
S
L
E
K
R
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
80.9
N.A.
86.7
85.2
N.A.
53.6
N.A.
62.3
62.3
N.A.
38.3
41.4
36.7
43.7
Protein Similarity:
100
N.A.
N.A.
83.9
N.A.
92.9
91.6
N.A.
61.9
N.A.
77
76.7
N.A.
53.2
57.9
56.4
59.4
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
20
20
N.A.
20
N.A.
6.6
6.6
N.A.
6.6
13.3
6.6
26.6
P-Site Similarity:
100
N.A.
N.A.
26.6
N.A.
26.6
26.6
N.A.
20
N.A.
26.6
20
N.A.
13.3
26.6
20
46.6
Percent
Protein Identity:
N.A.
31.8
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
48.6
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
24
8
24
0
0
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
8
0
24
16
0
0
0
8
8
0
8
0
% D
% Glu:
8
8
39
16
8
24
8
0
31
47
16
24
31
24
16
% E
% Phe:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
24
8
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
0
16
0
0
8
0
16
16
0
31
16
8
0
0
% K
% Leu:
8
8
8
0
8
0
8
24
0
0
8
8
0
0
16
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% N
% Pro:
16
31
8
8
16
16
24
8
16
16
16
16
24
8
24
% P
% Gln:
16
8
0
8
8
0
8
16
0
8
8
8
0
8
8
% Q
% Arg:
0
0
0
0
16
0
8
0
0
0
0
0
8
8
0
% R
% Ser:
0
8
16
24
0
0
0
0
0
16
0
0
8
8
8
% S
% Thr:
0
8
8
0
16
0
0
16
8
8
0
8
8
16
0
% T
% Val:
24
8
0
8
16
0
8
16
16
0
8
8
16
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _